Staff Scientist (AC-TAP) in Biomolecular Sciences at the Department of Biology, Faculty of Science, University of Copenhagen

We are looking for a highly motivated and independent staff scientist to support our efforts in research, student supervision and teaching on various projects in molecular biology and protein science. The position is open from January 1st, 2027.

Our research

You will be employed in the section for Biomolecular Sciences (BMS), which harbors 12 independent research groups. Research in the section covers a range of fundamental protein biomolecular topics primarily investigated in a cellular context. Techniques include NMR spectroscopy, computational biology, protein design and sophisticated directed evolution selection systems. You will be associated with two of the BMS research groups.

In the Hartmann-Petersen lab, the group investigates how cells maintain protein homeostasis through the protein quality control (PQC) system and how defects in these pathways contribute to disease. Research activities combine molecular genetics, functional genomics,



and advanced high-throughput technologies to dissect the mechanisms governing protein folding, degradation, and cellular stress responses. A central focus is the development and application of Deep Mutational Scanning (DMS) to systematically characterize the functional consequences of genetic variation at scale. By integrating DMS with genome-wide CRISPR screening and other multiplexed assays, the group aims to uncover sequence-function relationships, identify determinants of protein stability and degradation, and map the cellular pathways that influence variant effects. This work provides fundamental insights into PQC networks and contributes to improved interpretation of human genetic variation in health and disease.

In the Ellgaard lab, the focus is on the structure, function and evolution of newly discovered animal toxins from a variety of venomous animals. To produce these peptide toxins, the

📌 Staff Scientist (Chimbote)
🏢 Department of Pharmacy, University of Copenhagen
📍 Chimbote